She traded primarily between London and Hambro.

Amphitrite first appeared in Lloyd's Register in 1794 with Sanderman, master and owner, and trade London–Hamburg.

[1] Lloyd's Register for 1798 showed Amphitrite with Sanderman, master and owner, and trade London–Hamburg.

[2] Lloyd's List reported on 2 November 1798 that a French privateer had captured Amphitrite, Sanderson, master, as Amphitrite was sailing from Hambro to Havana.

The privateer sent Amphitrite into Havana.