At the time it was built there were no coaching connections by road, so for a number of years the station was particularly beneficial in providing an outlet for the trade in straw hats, Ampthill's speciality being the "Narrow Improved" version.

[1] The station closed in 1959 and the inhabitants were advised to use the "excellent alternative bus service."

About half a mile north of the station is Ampthill Tunnel, increased to two bores when the line was upgraded to four tracks in 1891.

[1] Trains on the Midland Main Line, electrified through the former station, still pass the site.

The area in which Ampthill station was situated is still visible today due to the widening of tracks where the now long gone platforms used to be.