[6][7] Subhash made her debut with the National Award-winning film and India's Oscar entry for the year 2004, Shwaas.

She has appeared in the Netflix Original series Selection Day (2018–19) and opposite Nawazuddin Siddiqui in Sacred Games (2019).

[13] While there, she appeared in various plays, including Urvashiam (1997), Bela Meri Jaan (1998), House of Bernada, Alba (1998), and Mrug Trushna (1999).

[13] Subhash portrayed the role of ex-bar dancer Lily in the Netflix series Bombay Begums, directed by Alankrita Shrivastava.

Directed by Sagar Sarhadi, whose 1982 film Bazaar was critically acclaimed, Subhash called the role a "dream come true".

[3] The same year, she played the title role in the television film Nirmala, directed by Gulzar, based on Premchand's novel of the same name.

Subhash was next seen playing various roles in TV shows, such as Zoka, Paaulkhuna, and most importantly, Awaghachi Sansaar, which aired on Zee Marathi.

[19] She became popular for her role of Aasawari opposite actor Prasad Oak, where she fights back against the atrocities laid upon her by her husband.

[20] In 2008, she appeared in a supporting role in Nandita Das's debut directorial venture Firaaq, based on the aftermath of the 2002 communal riots in Gujarat.

[21] Critically acclaimed, nationally as well as in various international festivals, the film showcased several notable actors including Naseeruddin Shah, Paresh Rawal, and Deepti Naval.

[26][27] "Whether I am tired, sad or depressed... my plays never fail to uplift my mood and always make me feel rejuvenated at the end of it.

Along with her film career, Subhash has acted in a number of theatre plays, including Sathecha Kaay Karayacha!

[29] In Ajuni Yeto Vaas Fhulana, director Chetan Datar paid tribute to veteran theatre personality Satyadev Dubey.

[13] They have acted together in many films, including Aaji, Zoka, Gandha, Masala, Nital, Valu, Badha, Vihir, and Gully Boy, and the play Kalokhachya Leki.