She subsequently starred in two of the highest-grossing Hindi films of their respective years, the comedy-dramas Zindagi Na Milegi Dobara (2011) and Yeh Jawaani Hai Deewani (2013), both of which garnered her nominations for the Filmfare Award for Best Supporting Actress.

Koechlin's commercial success continued with the supernatural thriller Ek Thi Daayan (2013) and the musical drama Gully Boy (2019), while also receiving praise for her performances in independent films, including Waiting (2015) and Ribbon (2017).

[15] Starring alongside Abhay Deol and Mahie Gill, Koechlin plays the role of Leni / Chanda, a young woman who turns to prostitution after a leaked sex tape scandal.

Co-starring Ranvir Shorey, Vinay Pathak and Ravi Kishan among others, the film opened to mixed-to-negative reviews from critics, as did Koechlin's performance as a manipulative woman who is abducted by two corrupt policemen.

[7] The first was Bejoy Nambiar's crime thriller Shaitan, alongside an ensemble cast of Rajeev Khandelwal, Gulshan Devaiah, Shiv Panditt, Neil Bhoopalam, Kirti Kulhari, Rajit Kapoor, Pawan Malhotra and Rajkummar Rao.

She played the role of a disturbed teenager and called it an "exhausting experience", saying that she felt drained while trying to, "get into a psyche of someone who does a lot of drugs and booze, has lost her mind a little bit and is very vulnerable".

[36][37] Revolving around the story of three childhood friends who take a three-week road trip in Spain, the film saw her portray a South Bombay interior designer, who is slightly possessive of her fiancé.

[61][62] Koechlin's commercial success continued with both of her 2013 releases, the supernatural thriller Ek Thi Daayan and the ensemble coming-of-age romantic comedy-drama Yeh Jawaani Hai Deewani.

[66][67][68] Ayan Mukerji's coming-of-age romantic comedy-drama Yeh Jawaani Hai Deewani, saw Koechlin star alongside an ensemble cast of Deepika Padukone, Ranbir Kapoor and Aditya Roy Kapur.

Saurabh Dwivedi of India Today wrote that "Koechlin steals the show with her perfect portrayal of a nagging girlfriend", and Rohit Vats of Hindustan Times noted that, although her character in the film felt a bit forced, she delivered a "charming" performance.

[84] In 2015, Koechlin starred in Shonali Bose's drama Margarita with a Straw, playing a young woman with cerebral palsy who leaves her home in India to study in New York City, unexpectedly falls in love, and embarks on a journey of self-discovery.

[88][89] She underwent a six-week training workshop with actor Adil Hussain, aimed at making her "body language seem natural", while also focusing on the speech pattern of patients with cerebral palsy.

[92] While Leslie Felperin of The Hollywood Reporter made a detailed note of her "bravura performance in both physical and emotional terms", Saibal Chatterjee deemed her "[simply] brilliant".

Sukanya Verma of Rediff.com called the film "absolutely riveting", and also lauded the "stunningly unhindered" Koechlin writing that she used her aura, "in the most mesmeric fashion to create a woman we sympathise with and wish well for".

[113] Koechlin appeared in two documentary films in 2016—Freedom Matters, a project aimed at spreading awareness on human trafficking, and Living Shakespeare, a BBC production where she drew parallels between Ophelia and Indian women.

[137] In 2019, Koechlin starred alongside Ranveer Singh, Alia Bhatt and Siddhant Chaturvedi in Akhtar's musical drama Gully Boy as a record producer who has an affair with the titular character.

[138] The same year, she ventured into OTT with the Amazon Prime Video romantic drama web series Made in Heaven (2019–present), which was a dark take on the Big Fat Indian Wedding, human nature and greater social dynamics in Delhi.

Starring alongside an ensemble cast of Sobhita Dhulipala, Arjun Mathur, Jim Sarbh, Shashank Arora and Shivani Raghuvanshi, Koechlin played the role of a woman deeply lodged in her insecurities under the guise of a confident socialite.

Later that year, she starred in the second season of Netflix's neo-noir crime thriller web series Sacred Games (2018–19) as a self-styled godwoman alongside Saif Ali Khan, Nawazuddin Siddiqui, Pankaj Tripathi and Ranvir Shorey.

In 2022, Koechlin starred in the English-language drama Goldfish, as a daughter attempting to confront the traumas of her childhood whilst tending to her mother suffering from dementia (played by Deepti Naval).

In dual roles, Koechlin plays the Argentine writer and intellectual Victoria Ocampo (a close associate of Tagore), and a young woman who is writing a research paper on him.

[157] Koechlin's other early stage appearances include Atul Kumar's Trivial Disasters, The Real Inspector Hound, Ajay Krishnan's Hair, where she plays Rapunzel, and Kapoor's Hamlet, The Clown Prince.

Koechlin, alongside Jacqueline Fernandez and Sakshi Malik led a group of women at an event, organised as part of the movement, to break the Guinness World Record of "Most people to hold the abdominal plank position" for 1 minute.

[172][173] Koechlin was the ambassador for Cottonworld's "Adopt-A-Tree" initiative, under which the brand provided its customers with viable seeds and instructions of planting a tree, urging them to give back to the environment.

[180] Video messages recorded by Koechlin and Kunal Kapoor, in which they voiced their support for the LGBTQ community were screened at the 2016 Delhi International Queer Theater and Film Festival.

[191] She has also sporadically recited An Intense Piece about the Truths of Womanhood, a soliloquy, on such events as the International Women's Day special at the India Today Conclave in March 2014 and the 2016 Kalyani Nagar meeting of the FICCI Ladies Organisation.

[200] The success of Printing Machine was followed by a second collaborative video for the Unblushed series, Noise, another original poem which was released on the company's YouTube channel on 22 June 2017 (World Music Day).

She suggested alternative readings that, among other things, disregarded the notions of a princess "[who] must never displease", a prince, who "has to be gentle and yet be a man" and interpreted a witch not as the "antagonist, but [...] as a strong woman misunderstood by the society".

[237] Such designers and photographers as the slow-process multimedia artist Riyas Komu and Elle couturier Amit Aggarwal have described Koechlin's persona as representative of "a sense of eclecticism" and "fresh, akin to a new wave" respectively.

[247] She was also the brand ambassador of the "Cinema For Care" section, aimed at creating awareness about disability issues at the All Lights India International Film Festival (ALIIFF) held in Thiruvananthapuram, Kerala in November 2015.