Amstel station is situated in the Omval business district which includes the Rembrandt Tower, the tallest skyscraper in the city, and the Leeuwenburg campus of the Hogeschool van Amsterdam.

Schelling of NS, the principal railway operator in the Netherlands, and John Leupen of the City of Amsterdam.

By eliminating the many level crossings in this part of the city, the project made an end to the many delays on these lines.

As Amstel station is situated southeast of the former Weesperpoortstation, it has become a major transport hub for the eastern and southern boroughs of Amsterdam.

The station hall also features a 1958 ceramic tile panel, also designed by Peter Alma and manufactured by H. Rijneveld.

Both outside and inside the building are two sculptures (1939) by Theo van Reijn, which are called 'Terugblik and Toekomst der Spoorwegen' (Translated: 'Retrospect and Future of the Railways") together.

[3] In 2006, the engineering building at the southern end of track 4 was decorated with a number of panels designed by Serge Verheugen.

The NS ticket barriers, however, remain opened permanently until the OV-chipkaart system is fully implemented in the rail network.