More than sixty percent of the population is concentrated in Anápolis, the regional center.

The largest cities are Anápolis, Inhumas, Jaraguá, and Itaberaí.

The most populous municipality is Anápolis with 325,544 inhabitants.

The largest municipality in land area is Jaraguá with 1,895.6 km2.

The area is slightly smaller than Puerto Rico or slightly less than three times the size of the American state of Rhode Island.