Ana Carrizosa Anderson is a Colombian-American microbiologist who is a professor at the Harvard Medical School.
Her research combines transcriptomics and systems biology to understand T-cell response to chronic disease.
[2] She moved to Harvard University for her doctoral research, where she studied T cell cross reactivity.
Immune checkpoint receptors are hijacked in cancer, where their high rates of expression on tumor T cells hampers the anti-tumor response.
The Treg cells that infiltrate tumor tissue up-regulate immune checkpoint receptors and have a highly suppressive phenotype.