[3][4] As a model, she has starred in advertisements and walked the runway for designers such as Giorgio Armani, Roberto Cavalli, Betsey Johnson, Kenzo, Hanae Mori, Alexandre Herchcovitch, Emanuel Ungaro, Lorenzo Riva, Leonard, Lolita Lempicka, Yves Saint Laurent, Yohji Yamamoto, Neiman Marcus, Schwarzkopf, Gai Mattiolo, La Perla, L'Oréal, Wella, Nivea, Valisere, Cia Marítima, Rosa Chá, Ellus, Cori, Vizzano, Equus Golden Lady, Adidas, Tic Tac,[5] Volkswagen,[6] LG, Sensodyne, Beauty Color,[7] Rommanel, Marcyn, Recco, Britânia, among others.

[9] In June 2004 at the São Paulo Fashion Week, she walked the runway for her own line of animal print bikinis in partnership with the brand Sais de Cor, carrying an Albino Python snake wrapped around her neck.

Hickmann organised two fashion shows for the girls, one with wedding dresses and the other with clothes made by a group of seamstresses from the community of Heliópolis.

[12][13] On 25 June 2016, she walked the runway for the first time in ten years as a special guest in the closing show of the Angola Fashion Week in Luanda.

[16] She currently distributes her own clothing, perfumes, bags, jewellery, watches, shoes, eyeglasses, sunglasses[17] and cosmetics lines,[18] and also manages a photography studio and a DJ agency.

[24] From 2005 to 2009, she co-hosted the daytime TV show "Hoje em Dia" ("Nowadays"), next to Britto Jr and Eduardo Guedes on Rede Record.

In 2009, she started hosting her own TV show, replacing Eliana on Tudo É Possível ("Everything is Possible"), on Sunday afternoons, also on Rede Record.

[26][27] From 2012 to 2014, she co-hosted the daytime TV show Programa da Tarde ("Afternoon Program") on Rede Record, (with Britto Jr and Ticiane Pinheiro).

[39] On 21 May 2016, Hickmann was a victim of attempted murder when Rodrigo Augusto de Pádua invaded the hotel room where she was and fired at her, her sister-in-law and her brother-in-law.