He served as the General Director of Russian Federal Space Agency in 2004–2011.

In 1991 he again earned an advanced degree in Moscow from the Military Academy, after which he was appointed to the head of the Russian Department of Defense research test site.

[1] Perminov has a PhD in engineering, and has authored more than 70 scientific papers and articles on space exploration.

[3] On 29 April 2011, Perminov was replaced with Vladimir Popovkin as the director of Roscosmos.

The 65-year-old Perminov was over the legal limit for state officials, and had received some criticism after a failed GLONASS launch.