Danielsen Lie played major roles in the 2021 films The Worst Person in the World by Joachim Trier, and Bergman Island by Mia Hansen-Løve.

[5] In March 2023 it was announced that he was set to work with Glenn Close on director Charlie McDowell's film adaptation of Tove Jansson's novel The Summer Book.

On 11 April 2011 he released This Is Autism, a concept album with music written, performed and produced by himself, loosely based on recordings from his childhood.

Anders Danielsen Lie is a medical doctor and in-between movies maintains his practice working as a general practitioner with patients in Oslo.

After shooting The Worst Person in the World in the fall of 2020, he started working as a medical supervisor for the COVID-19 vaccination center and contact trace team in the Nordre Aker borough of Oslo.

[6] In 2007 Danielsen Lie and psychologist Maria Øverås authored a Norwegian language non-fiction sexual education book for young adults (Sex og sånt, Gyldendal, ISBN 9788205370463).