Anderson's Corner, Virginia is located in James City County near the unincorporated community of Toano.
Located at the intersection of U.S. Route 60 and State Route 30, Anderson's Corner was the western terminus of State Route 168 a new four-laned highway also known as the Merrimack Trail which was established in the pre-World War II era to supplement the heavily traveled Route 60 through the Williamsburg where the Colonial Williamsburg Restoration funded by Abby and John D. Rockefeller Jr. had added to traffic, as well as the growing Virginia Peninsula area, connecting via harbor ferry with similarly designated roads in South Hampton Roads.
The newly completed two-laned Hampton Roads Bridge-Tunnel was designated Route 168 when it opened in 1957.
The new Tidewater Drive received the Route 168 designation after World War II.
As portions of Interstate 64 were completed in the late 1950s and 1960s, they occasionally bore a Route 168 designation for a period of time until substantial through service using the I-64 signage became more practical for use.