Andersonglossum virginianum, known as southern wild comfrey,[1] is a flowering plant in the borage family native to North America.

[1][3] It densely populates the central and southeastern parts of the U.S. and is often found in open uplands, such as in southern New England, from New York to Illinois, Louisiana, Oklahoma, and from the south to Florida.

[3] A closely related species, Andersonglossum boreale is disappearing from the southern part of its range in the United States.

Unlike A. virginianum, Andersonglossum boreale has petioles on its cauline leaves and its corolla lobes are not rounded and do not overlap.

[5][6] Pyrrolizidine alkaloids, hepatoxins capable of affecting grazing animals and humans, are synthesized by many borages including Andersonglossum officinale.