André-Eugène Pirson (21 March 1817 – 28 December 1881) was a Belgian liberal politician, civil servant, and former governor of the National Bank of Belgium (NBB) from 1877 until 1881.

Born in Dinant, he started his career in the army, but left after four years of service to become the State cashier's agent for the Société Générale de Belgique, first in Oudenaarde, and later in Tournai until 1850, when the National Bank of Belgium was established.

André-Eugène Pirson continued his career at the National Bank as an agent for the NBB in Tournai.

In 1855, he set up a discount office in Tournai and also worked as acommissioner and administrator of a number of savings banks.

During his term of office he was confronted by and economic recession and growing tensions within the Latin Monetary Union.