[3] André made his professional debut on 16 September 2020, coming on as a late substitute for Dodi in a 1–0 home win over Atlético Goianiense, for the year's Copa do Brasil.

André scored his first professional goal on 4 July 2021, netting a last-minute winner in a 1–0 away success over rivals Flamengo.

[8] Later that year, on 4 November, he started in the Copa Libertadores final with Fluminense against Boca Juniors, which ended in a 2–1 victory after extra time, to be his club's first title in that competition.

[9] On 30 August 2024, just before the transfer window closed, André joined Premier League club Wolverhampton Wanderers.

[11] On 20 June 2023, he made his international debut, coming off the bench in the 74th minute to substitute Lucas Paquetá, in a 4–2 defeat in a friendly match against Senegal.