[3] From 1999 to 2006 she was resident director at the Burgtheater,[4] staging Horváth's Der jüngste Tag, Kleist's Das Käthchen von Heilbronn, Friedrich Schiller's Maria Stuart and Don Carlos, Albert Ostermaier's Letzter Aufruf and Nach den Klippen, Tennessee Williams' Cat on a Hot Tin Roof, Anton Chekhov's The Cherry Orchard and Lessing's Minna von Barnhelm.
[3] Her directorial work at the Burgtheater from 2009 onwards included Motortown by Simon Stephens, Quay West by Bernard-Marie Koltès, Zwischenfälle (with scenes from Courteline, Cami and Charms), Kleist's Prinz Friedrich von Homburg in a co-production with the Salzburg Festival, Shakespeare's Hamlet, This Story of You by John Hopkins, Harold Pinter's The Birthday Party (in co-operation with the Salzburg Festival) and finally, Long Day's Journey into Night by Eugene O'Neill.
[3] In 2011, she directed Isaak Babel's Marija at the Düsseldorfer Schauspielhaus, in 2013 Ibsen's John Gabriel Borkman at the Schauspiel Frankfurt and in 2014, Pinter's The Caretaker at the Residenztheater in Munich.
[3] In the 2018/19 season Breth has been directing Die Ratten by Gerhart Hauptmann at the Akademietheater[5] and Jakob Lenz by Wolfgang Rihm at the festival of Aix.
[7][3] She also won the Schiller Prize of the City of Marbach in 2015 and Der Faust award in 2015 in the Musical Theatre Direction category for Jakob Lenz.