Andrea Matteo Palmieri (1493–1537) was an Italian Roman Catholic bishop and cardinal.
He was a cleric in Naples before being elected Archbishop of Averenza and Matera on 30 July 1518, with dispensation for not yet having reached the canonical age of 27.
During the pontificate of Pope Adrian VI, he spent his own money and solicited funds from his friends in the Knights Hospitaller to prepare troops to fight against the Ottoman Empire.
On 21 August 1528 he resigned the administration of Averenza and Matera in favor of his brother Francesco Palmieri.
Shortly before the cardinal's death, Charles V, Holy Roman Emperor named him governor of Milan.