[1] Polli blends art and science to create widely varied media and technology artworks related to environmental issues.

[2] Her works are presented in various forms, she uses interactive websites, digital broadcasting, mobile applications, and performances, which allows her to reach a wider audience.

[3] Additionally, Polli's installations, such as Particle Falls, have been displayed in multiple cities across the U.S., including Philadelphia, Detroit, and Pittsburgh, where they use real-time data to visualize environmental conditions like air quality, raising awareness about pollution and climate change.

In one of her key installations Atmospherics/Weather Works Polli used detailed climate models to recreate the sounds of two major East Coast storms: the presidents’ Day Snowstorm of 1979 and Hurricane Bob in 1991.

One of her other prominent works, Heat and the Heartbeat of the City involved creating sonifications based on the actual and projected climate data for Central Park.

[14] Another project, N. (pronounced n-point), developed in collaboration with Joe Gilmore, is a real-time multi-channel sonification and visualization of weather patterns in the Arctic.

This work uses a nephelometer to sample particulate matter in the air from a city street, displaying the data in real-time as changing light patterns every 15 seconds on the wall of Philadelphia's Wilma Theater.

[18] In another project, Polli collaborated with Rod Gdovic of WindStax, a Pittsburgh-based wind turbine manufacturer, to create the Energy Flow.