Andrew Reginald Nicholas Gerald Bonaparte-Wyse, CBE, CB (1 November 1870 – 1 June 1940) was an Irish civil servant and for many years the sole Roman Catholic in the Northern Ireland administration to rise to the rank of Permanent Secretary.
Andrew Reginald Nicholas Gerald Bonaparte-Wyse was born on 1 November 1870 in Limerick, Ireland.
He was the grandson of Sir Thomas Wyse, a Member of Parliament and educational reformer, and great-grandson of Lucien Bonaparte.
Described by the historian Joseph Lee as a "hardline Unionist", Bonaparte-Wyse remarked on the change of attitude in Dublin following the Easter Rising of 1916: "there is a very menacing tone among the lower classes who openly praise the Sinn Féiners for their courage and bravery".
In 1896, he married Mariya de Chripunov, the daughter of a Russian aristocrat; the couple had had three children; two daughters, Helen Victoria and Mary Alexandrine, and a son, William Lucien, who served in the Free French Navy during the Second World War.