[3] In February 1147, along with his older brother Alexios, he attended a church synod at the Palace of Blachernae, which deposed Patriarch Kosmas II Attikos.
[5][2] In Cilicia he was confronted by the local Armenian lord, Thoros II, who aimed to reassert the region's independence from the Byzantine rule.
[6] In 1162, Thoros' half-brother, Stephen, was found murdered outside the walls of Tarsus, after being invited by Euphorbenos to a banquet in the city the previous day.
Even though Stephen was a rival, this provided Thoros with a suitable pretext for attacking the Byzantine holdings in the area, although Euphorbenos strenuously denied any involvement in the deed.
[3][7] In the interest of unity against the Muslims, King Amalric of Jerusalem mediated between Thoros and the Byzantines, leading to Euphorbenos being recalled and replaced with Constantine Kalamanos.