Andrzej Grzymała of Poznań (died September 1466, Kraków) was a Polish academic and rector of the Cracow Academy in the 15th century.
He spent 1460–1462 in Italy, primarily in Rome, but perhaps also in Perugia, where he probably earned a doctorate in medicine in 1461.
In 1464/1465 he served as dean of the faculty of medicine in Cracow, and was twice elected rector of the university.
In addition to poetry and rhetoric, Grzymala also studied astronomy and wrote a text on the use of astronomical tables, titled Canonaes Tabularum Resolutarum.
They include copies of Eberhardus Bremensis's Laborintus, Geoffrey of Vinsauf's Poetria Nova, and Leonardo Bruni's Poliscene, which has a commentary possibly attributed to Grzymała.