That same year Nyman won the award for best actor at the 2006 Cherbourg-Octeville Festival of Irish & British Film for his role as Colin Frampton in Shut Up and Shoot Me.
[6] In 2007, Nyman appeared as one of the leads in the Frank Oz film Death at a Funeral, starring opposite Matthew Macfadyen, Ewen Bremner and Keely Hawes.
In 2008, he starred as Patrick, a sleazy reality show producer, in Charlie Brooker's E4 horror satire Dead Set,[7] and appeared in BBC Four's supernatural drama series Crooked House.
He did voice over work as the character Bag for the series Sarah & Duck and Chuggington, and portrayed a young Winston Churchill in the BBC drama Peaky Blinders.
In 2014 Nyman played the role of Charles Guiteau in the Stephen Sondheim musical Assassins at the Menier Chocolate Factory, and appeared in the film Automata with Antonio Banderas and Dylan McDermott.
In 2014, Nyman was one of 200 public figures who were signatories to a letter to The Guardian opposing Scottish independence in the run-up to September's referendum on that issue.