Localities with the oldest documentary attestation are Gura Bîcului, Teliţa, Mereni documented for the first time in 1443–1475.

The following centuries shows development in the economy (trade, agriculture, customs duties), and a significant demographic growth.

In 1812, after the Russo-Turkish War (1806–1812), is the occupation of Basarabia, Russian Empire during this period (1812–1917), there was an intense russification of the native population.

In 1918 after the collapse of the Russian Empire, Bessarabia united with Romania in the period (1918–1940, 1941–1944), the district was part of the Chişinău County.

Fauna typical of central Europe this mammals such as foxes, hedgehogs, deer, wild boar, ermine, ferret and more.

Of birds: owl, stork, hawk, sparrow, starling, crow, egret, partridges and others.

The district Anenii Noi operates: 65 artistic, two art schools, 18 teams, holding the title of the band model, 37 public libraries.

In health care population Anenii Noi District operates: 123 doctors, 356 average staff, nurses, 348 medical and auxiliary personnel.