Angélique des Méloizes (French pronunciation: [ɑ̃ʒelik de melwaz]; December 11, 1722- December 1, 1792) was a Canadian socialite, and the politically influential mistress of François Bigot, Intendant of New France 1748-1760.
Her mother was Françoise-Thérèse Dupont de Neuville, she was born in Quebec City.
Des Méloizes was married to the adjutant of that city, Michel-Jean-Hugues Péan.
She is known for her love affair with François Bigot, Intendant of New France 1748-1760, and for the influence over politics attributed to her during his tenure, for which she has been compared to Madame de Pompadour.
In their later years, the couple lived at Orzain near Blois in France.