He was born in Crete and migrated to Otranto, Southern Italy where he did most of his work.

[5] Bizamanos painted a very famous triptych which was exhibited in Rome at the Accoramboni Palace.

The left-wing shows Saint Jerome in the desert and the right features John the Baptist.

Another form of his inscription was Angelus Bizamanus Grecus Cadiotus Pinxit in Otranto.

In 1518, he was commissioned to create an altarpiece for the Confraternity of the Holy Spirit in Komolac, Dalmatia, a colony of Venice.