It is a part of the Angleton Independent School District located in south central Brazoria County.

The recently built high school is located at 1 Campus Dr. on the outskirts of Angleton.

The varsity football stadium and baseball field is located next to Angleton High School.

The Angleton High School Theatre program also includes the Speech & Debate team, which competes in UIL, TFA, and NSDA.

Angleton High School is a member of the Thespian Honor Society represented as Troupe 266.