Anime Midwest is an annual three-day anime convention held during July at the Hyatt Regency O'Hare and Donald E. Stephens Convention Center in Rosemont, Illinois.

[4] The convention typically offers anime screenings, artist room, concerts, cosplay masquerade contest, date auction, dealers room, fan panels, formal dance, guest autographs, karaoke, Maid Cafe, rave dances, tabletop gaming, video game tournaments, and workshops.

[11][12] Anime Midwest moved to the Hyatt Regency O'Hare in Rosemont, Illinois, for 2013.

[13] Guests Deadlift Lolita, FEMM, Fuki, and Zwei could not attend Anime Midwest in 2019 due to visa issues.

[36] Ryan Kopf, the organizer behind Anime Midwest and several other conventions, was banned from Anime Milwaukee during the 2018 convention due to a sexual assault allegation involving the Milwaukee Police Department.