He has played club rugby for Leicester Tigers, in the Aviva Premiership, and a season loan at Leeds Tykes, now Yorkshire Carnegie, in National Division One.
Following a loan period at Leeds, Tuilagi ended his contract with Leicester Tigers to join Yorkshire Carnegie full-time.
On 19 August 2008 Tuilagi was confirmed as the last signing that would be joining Guinness Premiership side Sale Sharks on a four-year contract.
[1] On 13 June 2011 Sale Sharks announced that Tuilagi had been released from his contract after three years[2] and on 29 November 2011 he joined Newport Gwent Dragons.
On 8 May 2014, Antielea returned to England as signed for Newcastle Falcons in the Aviva Premiership on a two-year contract from the 2014-15 season, where he will join with his brother, Alesana Tuilagi.