Anjana was born on 10 December 1978 to a Sindhi Hindu family[1][2][3] in Jaipur, to Preethi and Om Sukhani and has an older brother.

[citation needed] During the early years of her career, she was cast in a television advertisement for Cadbury Dairy Milk chocolates alongside the Bollywood superstar Amitabh Bachchan.

[5] She was also noted for her performance in the remixed Hindi music video for the song Ghar Jayegi.

Her other releases were Jai Veeru, Jashnn and her Kannada debut film Maleyali Jotheyali alongside Ganesh and Yuvika Chaudhary.

In 2016, Anjana made her debut in Marathi cinema opposite Swapnil Joshi in Laal Ishq,[7] a Sanjay Leela Bhansali Production directed by Swapna Waghmare Joshi.