[3] She was also known for roles in various commercials, including those for Good Seasons salad dressing, Newport cigarettes, Ivory Snow detergent, and Sterling beer.

Before starting on The Edge of Night, she played the leading role of another journalist, Elizabeth "Liz" Fraser Allen in the soap opera From These Roots (1958–61).

[3] For her work on the show, Flood was twice nominated for the Daytime Emmy Award in the category of Outstanding Lead Actress in a Drama Series, in 1982[5] and 1984.

She was cast in a succession of shorter-term and recurring roles, playing Ella Hobbs, a villain on Search for Tomorrow, who tried to kill the show's leading character, Joanne, and played a variety of society matrons on Another World (Rose Livingston, 1986–1987), One Life to Live (Mrs. Guthrie, 1991), and As the World Turns, recurring from 1992 to 1993 as business executive Ruth Mansfield.

In 1987, she joined the cast of All My Children playing the recurring role of Bitsy Davidson, Cecily's snooty mother, and was briefly under contract to the show.