Ann Louise Wagner (née Trousdale, September 13, 1962) is an American politician and former diplomat serving as the U.S. representative for Missouri's 2nd congressional district.

[7][8] After college, she worked in the private sector and held management positions at Hallmark Cards in Kansas City and Ralston Purina in St.

[9] Wagner entered Republican politics in 1990, heading the GOP's efforts during the decennial redistricting of Missouri.

[10] Wagner was elected to her first term of office as chair of the Missouri Republican Party in 1999, becoming the first woman to occupy the position.

Her six years as chairperson witnessed George W. Bush carry Missouri in both of his presidential bids and also saw the Republican Party win a majority of the state's congressional delegation.

"[12] On August 1, she was sworn in as Ambassador by U.S. secretary of state Condoleezza Rice in the Benjamin Franklin Room of the Harry S Truman Building.

She won the four-way Republican primary—the de facto election given the lack of support for Democratic nominee Glenn Koenen[17]—with 66% of the vote.

In her first bid for reelection, Wagner ran unopposed in the Republican primary and easily won the general election, increasing her margin of victory from 2012.

[22] Wagner was considered potentially vulnerable due to the surprisingly close margin in 2018 and President Donald Trump's unpopularity in suburban areas.

[25] In 2016, Wagner made headlines by withdrawing her endorsement for the GOP nominee for president, Donald Trump.

[30][31] Wagner was one of 126 House Republicans who signed an amicus brief in support of Texas v. Pennsylvania, a lawsuit filed at the United States Supreme Court contesting the results of the 2020 presidential election.