[3] As a state representative, Luetkemeyer chaired the Financial Services Committee and the House Republican Caucus and co-sponsored a statewide constitutional amendment defining marriage as being between a man and a woman, which was approved by 71% of Missouri voters in 2004.

He also worked on legislation to allow Missourians to carry concealed firearms, ban partial-birth abortions, and reform worker compensation laws.

In 2005, Governor Matt Blunt appointed Luetkemeyer Missouri Tourism Director, a post he held until he ran for the U.S. House of Representatives in 2008.

Luetkemeyer became a candidate for the open seat in the 9th Congressional District after incumbent Kenny Hulshof’s resignation in his unsuccessful bid for governor.

Luetkemeyer won the Republican primary with 39.7% of the vote against state representatives Bob Onder and Danie Moore, as well as Brock Olivo and Dan Bishir.

[6][7] Current regulations allow BHCs with assets of less than $500 million that satisfy other tests to incur higher amounts of debt than larger institutions in order to acquire other banks.

3329 would apply the less stringent standard to more BHCs by raising the asset limit to $1 billion and allow savings and loan holding companies to qualify.

[6] On June 26, 2014, Luetkemeyer introduced H.R.4986, which would end the controversial Operation Choke Point,[8] which was designed to limit the activities of money launderers but had come under criticism for alleged abuse.

[10][11] In December 2020, Luetkemeyer was one of 126 Republican members of the House of Representatives to sign an amicus brief in support of Texas v. Pennsylvania, a lawsuit filed at the United States Supreme Court contesting the results of the 2020 presidential election, in which Joe Biden defeated[12] incumbent Donald Trump.

The Supreme Court declined to hear the case on the basis that Texas lacked standing under Article III of the Constitution to challenge the results of an election held by another state.