After her launch at Whitby in 1781, Ann and Amelia, under the command of Captain John Popham, was at The Downs on 30 January 1782.

[6] She served as a transport or troopship to support Major-General Sir David Baird's expedition in 1800 to the Red Sea.

[7] Baird was in command of the Indian army that was going to Egypt to help General Ralph Abercromby expel the French there.

Captain John Seater replaced Livingstone in January 1805, and on 25 February sailed towards the East Indies.

[12] On 14 February 1807 Captain Wise and Mediator fell in with Bacchante, Commander James Dacres, in the Mona Passage.

Dacres had Dauphin come into the harbour there under her French flag, with Bacchante disguised as her prize, and Mediator, a former merchantman, appearing to be a neutral ship.

Wise had two men killed and 12 wounded as Mediator had been more heavily engaged than Bacchante in the exchange of fire with the fort.

Dacres estimated that French casualties had been high, but did not have a number as the Frenchmen took to the woods as the fort fell.

[12] In 1807 Captain George Reynolds replaced Wise, who had become ill and who remained in the West Indies for a little while to recuperate before returning home.

[19] On 11 April 1809 Woolridge, in Mediator, commanded the flotilla of fire and explosion ships that Admirals Gambier and Lord Cochrane sent in to Basque Roads to attack the fleet that was arrayed there.

The necessary combustibles came from three French chasse-marées, laden with tar and rosin, that the fleet had recently captured.

Mediator, with the benefit of the wind and a tide running at four knots, broke through the boom protecting the French fleet.

[c] King George presented Woolridge with a gold medal and chain, worth £100, that had been specially struck for the occasion.

[23] In 1847 the Admiralty authorized the award of the Naval General Service Medal with clasp "Basque Roads 1809" to all surviving claimants from the action.