[1][2] From the age of seven, Castillo enrolled into various acting schools in Barcelona and Madrid, later studying at Saint Joan Bosco Horta college.

[3] Castillo's acting debut was in 2009 on the television movie El enigma Giarcomo, on TV3, in which she played the role of Maiana.

In 2023, Castillo landed a main role in the romantic comedy series A Perfect Story and later that year, she starred as Mia in survival thriller film Nowhere.

[7] In 2024, she was reported to have been cast alongside Ester Expósito in Carlota Pereda's vampire dramedic thriller television series Death to Love.

[8] She also was announced to lead the cast of the comedy series Su majestad to portray Pilar, a young princess and future Queen of Spain.