She was the first professionally trained ballerina to be employed at the Royal Danish Theatre after its foundation, in 1755–63.
When the first ballet company was formed at the newly founded Royal Danish Theatre, she and her spouse were engaged as the first professionally trained performers there.
As an artist, she was a respected dancer, admired for her great flexibility and agile body.
As a person, however, she was talked about as the lover of the theatre director Christian Fædder, which caused accusations of nepotism, and her and her spouse's rivalry with the first Danish ballet dancer couple, Carl Vilhelm Barch and Marie Barch, attracted attention.
Anna Como is noted to have performed at the Drury Lane Theatre in London in 1775.