Her father, Psachie Frajlich, a technician, found himself in Lysva, in Perm Region, in USSR, while her mother, Amalia, ended up in Kyrgyzstan where Anna was born.

[7] In 1967–1969 (right after the so-called 6-day War in the MidEast), the Communist government in Poland engaged in an anti-Semitic campaign that spurred the last significant emigration wave of Polish Jews from the country.

Anna Frajlich was the only Polish journalist from the Radio Free Europe to whom Czesław Miłosz granted an interview after he became the 1980 Nobel Prize winner in Literature.

[15] Scholars who study Polish emigre poetry agree that prevalent focus of her poetry are the "themes of time, change, journeys, exile, home and habituation, tamed landscapes and remembered objects, spaces lost and regained"[16] as well as the "themes of exile, emigration, dislocation, and adaptation to new cultural contexts"[17] On October 24–25, 2016, the University of Rzeszów, which specializes in the study of post-war Polish émigré literature, hosted a conference "Tu jestem/zamieszkuję własne życie" dedicated to the life and work of Anna Frajlich.

[18] The conference was co-sponsored by the Institute of Polish Philology of the Jagiellonian University in Kraków, the most prestigious center of literary studies in Poland.

The conference program states, "Frajlich's life and work are a microcosm of the entire twentieth century and bear witness to its tragedies, particularly the Holocaust and the Cold War.