Born in Eskilstuna, Sweden, Nordqvist was a successful amateur golfer in both Europe and the United States.

[1] She made the cut at the Ricoh Women's British Open in both 2007 and 2008 and earned the Smyth Salver for low amateur honours in 2008.

[11] At the 2013 Solheim Cup, Nordqvist won her alternate shot match with Caroline Hedwall with a hole-in-one at the 17th hole, beating Morgan Pressel and Jessica Korda 2 and 1 during the Saturday morning session.

[13] At the 2016 U.S. Women's Open, Nordqvist lost to Brittany Lang in a playoff due to a rules violation, for touching the sand with the club in a bunker.

[14] In September 2017, she won her second major, The Evian Championship in France, after overcoming American Brittany Altomare in a play-off in horrendous weather conditions.

[18] Nordqvist won the 2022 Big Green Egg Open in The Netherlands, her first individual success on the Ladies European Tour outside of the majors.