Samokhina started her film career in the 1980s and quickly became popular due to her talent, beauty and charm.

She is best known as the leading actress in Yuri Kara's Barons of Crime (rus.

Воры в законе[2]), a most outlandish, brutal and controversial Soviet film, about mafia and corruption in the late USSR.

At the end of the 1990s, Samokhina stopped working in cinema, focusing primarily on her private life and restaurant business.

[3] In November 2009, Anna Samokhina was diagnosed with stomach cancer at a late stage.