She was the author of a book of meditations, Der treue Seelenfreund Christus, first published in Jena in 1658.

[1] Anna Sophia was born in Birkenfeld to George William, Count Palatine of Zweibrücken-Birkenfeld, and his first wife, Countess Dorothea of Solms-Sonnenwalde.

She succeeded to the abbey-principality during the Thirty Years' War, which ended in 1648, and her small territory suffered invasion of the Swedish army.

Anna Sophia I often came into conflicts with John George II, Elector of Saxony, and the Quedlinburg city council.

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