[1] She graduated in Modern Literature from Sapienza and in 2000 moved to Paris to work on her doctoral thesis on the aesthetics of cinema.
[2] She has made a name for herself as a filmmaker after a series of successful short films that have screened at influential film festivals: La troisième fois (2006), Andante Mezzo Forte (2007), À la lune montante (2009), Tre ore (2010), Dans le coeur des grands (2012).
[3][4] In 2013, she filmed a documentary L'anima del Gattopardo about Luchino Visconti, made for Ciné+ and RAI channels.
[8][9] Her sophomore feature, a dark comedy Rossosperanza, was screened at the 76th Locarno Film Festival.
[10] For Rossosperanza, Zambrano was honoured with the Titrafilm Award at 2022 Les Arcs Film Festival.