The title then passed by marriage to Anne's maternal uncle, Richard Neville, the famous 'Kingmaker' of the later Wars of the Roses.

Upon the death of King Henry VI's uncle Humphrey, Duke of Gloucester, on 23 February 1447, Anne also succeeded to the lordship of the Channel Islands, which had been previously entailed on her father.

Both girls became wards of Anne's maternal step-great-grandmother, Alice Chaucer (widow of Thomas Montagu, 4th Earl of Salisbury, and a lady-in-waiting to Queen Margaret of Anjou) and William de la Pole, shortly to be Duke of Suffolk, who intended Anne to marry his own heir,[4] John de la Pole (1442–1492).

[9] John went on to marry Elizabeth of York, sister to the later kings Edward IV and Richard III.

Margaret married Edmund Tudor, 1st Earl of Richmond, and became the mother of King Henry VII.