Her subject material consisted mainly of birds, fruit and flowers painted in a realistic style.
[1] Her mother's name is unknown but her father was William Byrne, a notable engraver who specialized in landscapes.
Anne Frances Byrne and her siblings grew up helping in their father's engraving shop and learned artistic techniques from him before going off on their own to study under masters.
[1] She had a rocky relationship with the academy due to the sexism that was predominant in the art world and in society at the time.
Byrne became a full member of the Royal Watercolour Society in 1809, withdrew her membership in 1813, rejoined in 1821, and left again in 1834.
The effect is still noticeable today due to the lack of documentation of Anne Frances Byrne and her contemporaries.