In July 1368, she married John Hastings, 2nd Earl of Pembroke.
They had one son, John Hastings, 3rd Earl of Pembroke.
Her husband and father both died in 1375, and she became suo jure Baroness Manny (her one brother having died in his youth).
[1] Shortly before her death in 1384, Anne was made a Lady of the Garter.
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