"[3] Kauffman's past regional productions include Body Awareness by Annie Baker (2012) at the Wilma Theater;[4] and Pulitzer Prize finalist Becky Shaw by Gina Gionfriddo (2009); The Flea and the Professor by Jordan Harrison at the Arden Theatre Company (2011); Six Degrees of Separation by John Guare at the Williamstown Theatre Festival (2010); We Have Always Lived in the Castle by Adam Bock and Todd Almond at Yale Rep (2010); The Communist Dracula Pageant by Anne Washburn at ART (2008); Expecting Isabel by Lisa Loomer and Doubt by John Patrick Shanley at Asolo Repertory Theatre (2007); Act A Lady by Jordan Harrison at the Humana Festival of New American Plays (2006);[5] and Typographer's Dream and Shaker Chair by Adam Bock (2005).
The reviewer for Time magazine wrote: "She [Kauffman] serves the play wonderfully, with a light but firm hand, for a tense, almost breathtaking hour and a half.
"[10] Past Off-Broadway productions include Maple and Vine by Jordan Harrison (2011) and Pulitzer Prize finalist play Detroit by Lisa D'Amour (2012) at Playwrights Horizons;.
[11] Stunning by David Adjmi (2009) and Slowgirl by Greg Pierce (2012) at LCT3 ;[12] You'd Better Sit Down: Tales From My Parents' Divorce (Written with The Civilians) at The Flea Theater (2012); This Wide Night by Chloe Moss by Naked Angels Theater Company (2010); Sixty Miles to Silver Lake by Dan Le Franc at Soho Rep (2009); Have You Seen Steve Steven by Ann Marie Healy with 13P (2007); God's Ear by Jenny Schwartz at The Vineyard and New Georges (2007); and The Ladies by Anne Washburn at the Cherry Lane Theater and Dixon Place (2004).
Ben Brantley, in his review for The New York Times, noted the "beautifully acted production...directed with probing sensitivity by Anne Kauffman.
[21] She is a Sundance program associate, a usual suspect at New York Theatre Workshop, an alumna of The Drama League Directors Project and Soho Rep Writers and Directors Lab, a current member of Soho Rep's Artistic Council, Lincoln Center Directors Lab, a founding member of the Civilians, an associate artist with Clubbed Thumb and co-creator of the CT Directing Fellowship, and member of New Georges Kitchen Cabinet.
Kauffman directed the 2023 production of Lorraine Hansberry's The Sign in Sidney Brustein's Window starring Oscar Isaac and Rachel Brosnahan at the Brooklyn Academy of Music.