She appeared in the serial A Country Practice as vet Anna "Lacey" Newman and All Saints as Julie Archer and the award-winning ABC mini-series Simone de Beauvoir's Babies.
[citation needed] She has appeared in the feature films Daydream Believer (1992), Willful (2001) and with John Malkovich in Disgrace.
In addition, Anne has been assistant director at ACA for the 2012, 2014 productions of Reality Bytes.
[citation needed] Between 2006 and 2011, Looby conceived, developed and produced Breast Wishes.
[citation needed] She has taught acting-for-camera and Shakespeare for Beginners at both the NIDA summer school and Theatre Nepean UWS.