[11] Moscona completed her clinical and research training at Mount Sinai Health System in New York City.
She was promoted to tenured professor in 2001 and served as chief of pediatric infectious diseases and vice chair for research until 2005.
Moscona's research focuses on understanding how viruses enter human cells and how to use this knowledge to design better tools to prevent viral infection.
[21][22][23] Her research has been featured in outlets including Nature, Science, the New England Journal of Medicine, the New York Times, CNN, NBC, ABC and The Hill.
[24][25][26] On November 5, 2020, the New York Times reported that Moscona's research group had collaboratively developed “A nasal spray that blocks the absorption of the SARS-CoV-2 virus...” and that it had “...completely protected ferrets it was tested on, according to a small study...”[27] According to the article, the therapeutics are patent pending and awaiting market production.