Anne O'Brien, Countess of Inchiquin and 2nd Countess of Orkney (born Lady Anne Hamilton; 1696 – 6 December 1756) was a Scottish noblewoman and the eldest daughter of Field Marshal George Hamilton, 1st Earl of Orkney, and his wife, the former Elizabeth Villiers.
She became Countess of Inchiquin, through her marriage to her first cousin William O'Brien, 4th Earl of Inchiquin,[1] the O'Brien, Chief of the Name, Prince of Thomond, and Lord of Dál gCais.
[2] Their daughter, Lady Mary (c. 1721–1790), succeeded her mother in the earldom of Orkney.
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