Roumanoff started her career in the television program La Classe on France 3, alongside Fabrice, Lagaf' and Jean-Marie Bigard in 1987.

Roumanoff became part of the team of French TV show Rien à cirer on France Inter with Laurent Ruquier in 1991.

In 2001, Roumanoff was the French voice of Coco la bouche in the animated feature Rugrats in Paris: The Movie.

In 2003, her show Follement Roumanoff had a 13-month run at the Bobino Theater in Paris, then she started a tour in France and Quebec.

From September 2007, she made a comic forum on the news, entitled On ne nous dit pas tout in the show Vivement Dimanche, hosted by Michel Drucker.