Anne Elizabeth Trefethen FREng is Pro Vice-Chancellor (People & Digital), and professor of Scientific Computing at the University of Oxford.

[2] On 1 June 2018, Trefethen joined the board of the UK Statistics Authority as a non-executive director.

She was appointed the university's first chief information officer in March 2012 until October 2017, prior to which she served as Director of the Oxford e-Research Centre (2006–2012).

[5][6] and Co-Director of the Institute for the Future of Computing, part of the James Martin 21st Century School.

[6][7] From 1997 - 2001 she was Vice-President for Research and Development at Numerical Algorithms Group (NAG) Ltd. Trefethen spent 1988 - 1997 in the US at Thinking Machines Corporation and was Associate Director for Scientific Computational Support at the Cornell Theory Center.