The couple lived in a polygamous marriage arrangement as practiced by Islamic custom and Muluzi was also married to Patricia Shanil Muluzi from 1989.

[5] On 15 March 1999, Muluzi announced officially the separation from her after 30 years of marriage.

He then remarried Patricia Shanil Muluzi in a formal ceremony to mark her new position as the official first lady.

Up until their separation in March 1999, Muluzi lived with Anne in the State House in Blantyre.

[7] Her first born daughter, Esme Atweni Muluzi Malisita, died after lightning struck her on December 12, 2016.