[1] She also DJed in various locations, including hosting her AMP (Annie Mac Presents) Lost and Found venues in places like Ibiza.

[5] While she was on maternity leave her radio show was presented by MistaJam and then Mac returned to the station on 12 June 2017.

She previously hosted BBC Switch with close friend and fellow DJ Nick Grimshaw on Sunday evenings from 19:00 to 21:00 until 21 March 2010.

After this date, they moved to 22:00 – midnight with a new show simply called Nick Grimshaw and Annie Mac.

Annie made regular appearances as a feature presenter on BBC Two's The Culture Show, giving her opinions on the latest music offerings.

[11] She appeared on Never Mind the Buzzcocks in January 2006 and she co-presented Top of the Pops on 18 June 2006 with Reggie Yates and on 11 July 2006 with Rufus Hound in a T in the Park special.

[13] In August 2012, Annie Mac was one of the DJs selected by Channel 4 to hold a live six-hour, televised House Party on Bank Holiday Friday.

On 31 December 2012, Annie Mac was one of the DJs selected by Channel 4 to hold a live six-hour, televised New Year's House Party.

[18] In January 2017, Mac presented a BBC Three programme called Who Killed the Night investigating the status of British nightclubs following many closures, notably the Fabric closure and reopening and property developments on sites of former clubs, visiting the site of former Kings Cross club Bagleys/Canvas.

[23] On 20 April 2021 Mac announced her departure from Radio 1 after 17 years, citing the need to spend more time with her husband Toddla T and their children.

[24][25][26] In May 2023, Mac released her second novel, The Mess We're In, a coming-of-age story about Dubliner Orla who moves in with her friend's band in London and tries to juggle pursuing music, partying and her job at an Irish pub.

Annie was the second support act to play on the day, taking to the stage at around 3:30pm, preceded by Mitch Rowland, and followed by Inhaler (band) and Wet Leg.